LinkyLong list, so I'll just pick and choose a few here.
Outstanding Innovation in Gaming
* Braid - Microsoft Game Studios - Number None
* Left 4 Dead - Valve Software - Valve Software
* LittleBigPlanet - Sony Computer Entertainment America - Media Molecule
* Spore - Electronic Arts - Maxis
* Wii Fit - Nintendo - Nintendo
Outstanding Achievement in Sound Design
* Dead Space - Electronic Arts - EA Redwood Shores
* Gears of War 2 - Microsoft Game Studios - Epic Games, Inc.
* LittleBigPlanet - Sony Computer Entertainment America - Media Molecule
* Prince of Persia - Ubisoft - Ubisoft Montreal
* Wipeout HD - Sony Computer Entertainment America - SCE Studios Liverpool
Computer Game of the Year
* Fallout 3 - Bethesda Softworks - Bethesda Game Studios
* Left 4 Dead - Valve Software - Valve Software
* Mass Effect - Electronic Arts - Bioware
* Spore - Electronic Arts - Maxis
[Spore? Really?] * World of Warcraft: Wrath of the Lich King - Blizzard Entertainment - Blizzard Entertainment
Outstanding Achievement in Game Design
* Fable II - Microsoft Game Studios - Lionhead Studios
* Fallout 3 - Bethesda Softworks - Bethesda Game Studios
* Gears of War 2 - Microsoft Game Studios - Epic Games, Inc.
* Left 4 Dead - Valve Software - Valve Software
* World of Goo - Nintendo - 2D Boy
Overall Game of the Year
* Fallout 3 - Bethesda Softworks - Bethesda Game Studios
* Grand Theft Auto IV - Rockstar Games - Rockstar North
* Left 4 Dead - Valve Software - Valve Software
* LittleBigPlanet - Sony Computer Entertainment America - Media Molecule
* Metal Gear Solid 4: Guns of the Patriots - Konami Digital Entertainment, Inc. - Kojima Productions