I can't really say, I haven't played it.
About making games more accessible, there's those game gimmicks many have when dealing with "death."
With PoP, I think what Cobra is referring to is Prince's helper, Elika. I don't think there's an option to turn off her support for help -- it would be a good idea for veteran PoP players and hardcore gamers who want more of a challenge to be able to turn her support off. Anyways, any jump you miss or if you need some sort of assist -- boom, she magically grabs you and saves you. As interesting as that mechanic might be and as cool as that might be, in some regards -- do veteran PoP players and hardcore gamers need her saving you every single time? Doesn't that kind of stop the challenge of the game? If a patch came out which allowed the player to turn her support off, I'm sure platformer veterans would rejoice to have the option to throw more challenge in their platforming.
No, I don't have PoP 2008...yet -- but I know plenty about the Elika mechanic already.
When you die in Assassin's Creed for whatever reason -- whether you get killed in battle or say miss a huge jump which takes a wicked long fall to crash to your death -- it sends you back to your last auto-save. Basically, the game auto-saves anytime you perform a side quest, find a flag, and do a main quest thing. I think many hardcore gamers would prefer that kind of mechanic.
Bioshock's another example here. The Vita Chamber -- anytime you die, you get sent back to the nearest one -- which are littered all over the gameworld. And also, when you die, whatever remaining health the enemy has left, it still remains. So, you could die 15 times on Hardest difficulty, it'd only be a matter of time before you slay same enemy you're battling. In a patch though, 2K Boston did give the option for those chambers to be turned off -- since people wanted it so bad. Kudos, 2K.
About inaccessible areas, see Fable/Fable TLC. All these areas in the game, you can really only move around on a "pathway/road" to get to another area. You can't actually walk in the actual woods itself in some areas, but can only walk on that "pathway." It's not like an open world Oblivion where you can walk basically anywhere on the map -- even in the woodsy areas littered with trees galore around you while not walking on some "road" to get you to your next area.