Well, New Vegas is currently at 25% off at ~$38.
First of all, you are the man and you know why.
I did see New Vegas on there, and was tempted, but I'm going to hold off for a couple of reasons. 1.) Huge backlog of games. I think I've played my 2.) I'm pretty sure that the Holiday Sale is special in that there's a huge selection of games on sale for the duration of the week, but there's also daily deals of high profile games (Super Meat Boy) which have an additional discount for 24 hours. I'll see what comes up during the week and worst case scenario, get New Vegas for 25% off at the end of the sale.
Anyways, I picked up Oddboxx, Lara Croft and the Gaurdian of Light, and The Misadventures of PB Winterbottom ($0.49). Total Damage: $20. Also, some nice person gifted Super Meat Boy to me. Currently thinking about a couple more such as the newest Prince of Persia game.