So I finally had time to get in a few games of this. I haven't made it past floor 3 yet haha. There's tons of items. Some are usable, some give you upgrades, some are cosmetic, and I think some don't do anything.
play 1: I got a wire coat hanger, which ended up stuck through my head. I also picked up a needle called "the virus" which gave boils and made me look sickly.
play 2: I got a needle that gave me "roid rage", which made me permanently move faster for the rest of the game.
play 3: I got "technology", which gave me an electronic eye that shoots lasers instead of tears. I also got roid rage and something called "boom" that put a fuse coming out of my head like a bomb.
EDIT - A little more detail on how the game plays:
you use WASD to move, and the arrow keys to shoot in the 4 cardinal directions. Each floor of the basement has several rooms, each room is one screen (no scrolling), and the number of rooms and arrangement of them is randomized. You can drop bombs to blow up rocks that block off items, but they're limited so you can't always get everything. You also collect keys to open doors and chests, and coins to spend at item shops.